Summary Nomenclature

Congenital Disorders of Glycosylation or CDG (Last updated:26-11-2001)

ALG3T

Group/type Defect and defective gene Acronym
Group I  Defects in N-linked protein glycosylation due to deficiencies in the assembly of the dolichylpyrophosphate linked oligosaccharides and/or its transfer to asparagine residues on the nascent polypeptides. CDG-I
Type Ia Phosphomannomutase PMM2 CDG-Ia
Type Ib Phosphomannose isomerase MPI CDG-Ib
Type Ic Dolichyl-PP-Glc:Man9GlcNAc2-PP-dolichyl alpha1,3-glucosyltransferase ALG6 CDG-Ic
Type Id Dolichyl-PP-Man:Man5GlcNAc2-PP-dolichyl alpha1,3-mannosyl-transferase ALG3 CGD-Id
Type Ie Dolichol-P-Man synthase 1 DPM1 CDG-Ie
Type If Mannose-P-dolichol utilization defect1 MPDU1 CDG-If
Group II Defects in the processing of N-glycans or addition of other glycans to proteins CDG-II
Type IIa UDP-GlcNAc:alpha-6-D-mannoside beta-1,2-N- acetylglucosaminyltransferase II (GnT II) MGAT2 CDG-IIa
Type IIb Glucosidase I GCS1 CDG-IIb
ype IIc GDP-fucose transporter 1 FUCT1 CDG-IIc
Type x Genetic basis unknown CDG-x